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Tabebuia impetiginosa Standley

Description

It is a native tree species of America, where it grows from Paraguay and northern Argentina to Mexico; it is currently distributed mainly in Bolivia and northwestern Argentina. It prefers sandy and humid soils. It has very showy and characteristic pink flowers, which appear when it is still devoid of foliage in late winter. Its wood is used in construction, and medicinal properties are attributed to the infusion of its bark.

Part used

The inner part of the bark is used and, occasionally, the leaves.

Main constituents

  • Naphthoquinones: lapachol (3-4 %), α and β-lapachone, tabebuina, tectoquina.
  • Tecomine (alkaloid).
  • Essential oil (0.55-1.50 %): mainly sesquiterpenes.
  • Others: anisaldehyde, anthraquinones, rutinoside, coenzyme Q, tannins, quercetin, lignans, vanillin, vanillic acid.

Pharmacological action

  • Astringent and antidiarrheal.
  • Antifungal: especially against candida.
  • Hypoglycemic and hypotensive.
  • Antipsoriatic.
  • Antitumor.
  • Anticoagulant.

Indications

  • Coadjuvant in type 2 diabetes.
  • Diarrhea.
  • Candidiasis.
  • Psoriasis.

Contraindications

  • Allergy to the plant.
  • Pregnancy and lactation.

Side effects

  • May darken the color of urine.
  • At doses higher than recommended may cause digestive discomfort or dizziness.

Drug interactions

Anticoagulants and antiplatelet agents.

Precautions

Discontinuous treatments are recommended: up to 1 month and rest 2 weeks before starting a new intake.

Bibliography

Monografía de la SEFIT (Sociedad Española de Fitoterapia).

Jianmei Zhang, S.Triseptya Hunto, Yoonyong Yang et al. Tabebuia impetiginosa: A Comprehensive Review on Traditional Uses, Phytochemistry, and Immunopharmacological Properties. Molecules 2020, 25(18), 4294.

J. Rubén Gómez Castellanos1, José M. Prieto, Michael Heinrich. Red Lapacho (Tabebuia impetiginosa). A global ethnopharmacological commodity?. Journal of Ethnopharmacology 121 (2009) 1–13.

Beatrice N. Kiage-Mokua, Michael de Vrese, Jürgen Schrezenmeir. Cardioprotective and Lipid Lowering Effects Tabebuia Impetiginosa (Lapacho Tea) on Male Rats Fed A High Fat and Fructose Diet.

Giacomelli I, Scartoni D, Fiammetta M, Baki M, Zei G, Muntoni C, et al. Oral lapacho-based medication: an easy, safe, and feasible support to prevent and/or reduce oral mucositis during radiotherapy for head and neck cancer. Nutr Cancer. 2015;67(8):1247-53.

Muller K, Sellmer A, Wiegrebe W. Potential antipsoriatic agents: lapacho compounds as potent inhibitors of HaCaT cell growth. J Natural Prod 1999; 62 (8): 1134-6.